Allelic polymorphism in transcriptional regulatory regions of HLA-DQB genes.
نویسندگان
چکیده
منابع مشابه
Allelic polymorphism in transcriptional regulatory regions of HLA-DQB genes
Class II genes of the human major histocompatibility complex (MHC) are highly polymorphic. Allelic variation of structural genes provides diversity in immune cell interactions, contributing to the formation of the T cell repertoire and to susceptibility to certain autoimmune diseases. We now report that allelic polymorphism also exists in the promoter and upstream regulatory regions (URR) of hu...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1991
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.173.1.181